Diabetic and Insulin Coma

Low Dose Insulin Regimen for Diabetic Coma

Introduction Low dosage insulin regimens for diabetic "comas" have recently attracted considerable attention (Alberti, Hockaday and Turner, 1973; Page et al, 1974; Kidson et al, 1974; Semple, White and Manderson, 1974). These regimans have all originated from established diabetic centres, however the simplicity of these regimens, especially the intra muscular regimen (Alberti et al, 1973), woul...

Treatment of diabetic coma with small intravenous insulin boluses.

The clinical efficacy of small intravenous boluses of insulin in treating diabetic decompensation was tested in 23 patients presenting in either a ketoacidotic or a nonketotic diabetic coma. In addition to the usual ionic and fluid replacement, the patients received hourly intravenous injections of insulin 5 IU. This dose lowered blood glucose levels in all but two patients. In the patients who...

The management of diabetic coma.

The "third coma" in diabetes: diabetic coma without ketoacidosis.

THE COMPLEXITIES of the diabetic syndrome are underlined by the fact that diabetic coma may occur without obvious ketoacidosis. The position has recently been summarised in a leading article in the British Medical Journal (1965). To the first two comas met with in diabetes, namely diabetic coma with ketosis and hypoglycaemic coma due to excess insulin, must then be added a third type of coma. T...

Insulin Coma Treatment : Facts & Controversies

An appetite simulating effect has been attributed to the hypoglycemic action of insulin and this hormone was commonly employed previously to induce a gain in weight. This appetite stimulating effect was first observed by Pitfield in 1923. His paper was followed by a series of other reports which were more or less confirmatory in nature and showed the usefulness of insulin in malnutrition. These...